产品详细

采用多波长激光对外泌体、病毒等纳米材料样品中的所有颗粒进行完整、详细的分析。


外泌体、病毒和纳米颗粒都具有较宽的粒径分布,这使得传统的纳米颗粒追踪分析 (NTA)仪无法准确测量它们的粒径分布。ViewSizer 3000的三个激光器可同时工作,可在同一样品中收集各种尺寸的最准确的分布和浓度信息。如果某一颗粒来自某一激光的散射光信号太强使检测器达到饱和,软件会自动使用来自较低功率激光器的数据来确保获得最准确的尺寸和浓度信息。另一方面,当来自某一激光的散射光信号太弱而无法检测时,软件会使用更高功率激光的数据来准确跟踪颗粒。


交叉污染是所有分析中都存在的问题。简化清洁意味着彻底清洁。易于拆卸的样品池可以拆卸以进行快速、彻底的清洁,从而获得更好的数据。


摆脱传统 NTA 的限制


准确灵敏的分析,无交叉污染


请联系我们获取更多信息


概要


ViewSizer 3000 使用纳米颗粒追踪分析技术 (NTA) 的最新进展来准确确定颗粒属性!


粒径测量范围:10 nm- 15µm,具体范围取决于样品

ViewSizer 通过多激光纳米颗粒追踪分析技术 (NTA) 得到颗粒粒径及粒径分布。多个激光器可分析同一样品中各种不同尺寸的颗粒,分辨率更高。

浓度测量范围:5 x 106 - 2 x 108 颗/mL

NTA 可用于对测量体积中的颗粒进行计数。该测量方法可校正粒径对有效测量体积的影响。

无交叉污染

样品池可完全拆卸,拆卸后清洗更方便彻底。拆卸、清洁和重新组装比冲洗流通池更快。此外,配备多个样品池可样品测量通量,也可分配给共享(核心)设施中的各个小组。


ViewSizer 3000相关文献:

Biological characterization using protein crystal measurements https://bioprocessintl.com/analytical/product-characterization/biological-characterization-using-protein-crystal-measurements/
A lipase-independent pathway of lipid release and immune modulation by adipocytes https://science.sciencemag.org/content/363/6430/989
Application of a novel new multispectral nanoparticle tracking technique https://iopscience.iop.org/article/10.1088/1361-6501/aab940/meta
Biophysical characterization of polydisperse liposomal adjuvant formulations https://doi.org/10.1016/j.bbrc.2020.05.156
Characterisation of particles in solution – a perspective on light scattering and comparative technologies https://doi.org/10.1080/14686996.2018.1517587
Cyclodextrin Reduces Intravenous Toxicity of a Model Compound https://doi.org/10.1016/j.xphs.2019.01.004
Development and anti-Candida evaluation of the vaginal delivery system of amphotericin B nanosuspension-loaded thermogel https://doi.org/10.1080/1061186X.2018.1434660
Electrochemical sensor based on F,N-doped carbon dots decorated laccase for detection of catechol https://doi.org/10.1016/j.jelechem.2019.03.071
Light scattering by pure water and seawater: the depolarization ratio and its variation with salinity https://doi.org/10.1364/AO.58.000991
Lipid Nanoparticle-Delivered Chemically Modified mRNA Restores Chloride Secretion in Cystic Fibrosis https://doi.org/10.1016/j.ymthe.2018.05.014
Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells https://doi.org/10.1038/s41598-020-67039-w
Multifunctional Nanocomposites Based on Liposomes and Layered Double Hydroxides Conjugated with Glycylsarcosine for Efficient Topical Drug Delivery to the Posterior Segment of the Eye https://doi.org/10.1021/acs.molpharmaceut.8b01136
Particle size analysis of polydisperse liposome formulations with a novel multispectral advanced nanoparticle tracking technology https://doi.org/10.1016/j.ijpharm.2019.06.013
Review of nanoparticles in ultrapure water: definitions and current metrologies for detection and control https://www.ultrapuremicro.com/articles/review-of-nanoparticles-in-ultrapure-water-definitions-and-current-metrologies-for-detection-and-control
Spark erosion as a high-throughput method for producing bimodal nanostructured 316L stainless steel powder https://doi.org/10.1016/j.powtec.2018.01.012
Synthesis and Characterization of EGFR-Targeted Immunoporphysomes http://hdl.handle.net/1807/89548
Synthesis of Ultrasmall Synthetic Melanin Nanoparticles by UV Irradiation in Acidic and Neutral Conditions https://pubs.acs.org/doi/abs/10.1021/acsabm.9b00747
Nanoparticle Tracking Analysis for the Quantification and Size Determination of Extracellular Vesicles | Protocol (jove.com) https://doi.org/10.3791/62447
Isolation and characterization of EV in Saliva of Children with Asthma https://evcna.com/article/view/3962
Spinal cord injury alters microRNA and CD81+ exosome levels in plasma extracellular nanoparticles with neuroinflammatory potential https://doi.org/10.1016/j.bbi.2020.12.007
Skeletal muscle tissue secretes more extracellular vesicles than white adipose tissue and myofibers are a major source ex vivo but not in vivo https://doi.org/10.1101/2020.09.27.313932
Human milk extracellular vesicle miRNA expression and associations with maternal characteristics in a population-based cohort from the Faroe Islands https://www.nature.com/articles/s41598-021-84809-2
Purification of Cas9 - RNA Complexes by Ultrafiltration https://doi.org/10.1002/btpr.3104


配置

测量范围

10 nm - 15 μm

典型样品体积

350 µL - 1.25 mL

典型样品浓度(取决于样品)

5 x 106 to 2x108 颗/mL

样品温度范围(可控)

10° C - 50° C +/- 0.1° C

外观尺寸

55 cm W x 66 cm D x 35 cm H

重量

27 kg

工作环境

15° C - 30° C,湿度 < 85% RH